TESTS OF ASSOCIATION BASED ON GENOMIC WINDOWS CAN LEAD TO SPURIOUS ASSOCIATIONS WHEN USING GENOTYPE PANELS WITH HETEROGENEOUS SNP DENSITIES

Tests of association based on genomic windows can lead to spurious associations when using genotype panels with heterogeneous SNP densities

Abstract Dense bekindtopets.com single nucleotide polymorphism (SNP) panels are widely used for genome-wide association studies (GWAS).In these panels, SNPs within a genomic segment tend to be highly correlated.Thus, association studies based on testing the significance of single SNPs are not very effective, and genomic-window based tests have been

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Determining The Role of MicroRNAs in Self-Renewal, Metastasis and Resistance to Drugs in Human Gastric Cancer Based on Data Mining Approaches: A Systematic Review

Gastric cancer (GC) is one of the leading causes of cancer-related deaths worldwide.The major problems of patients with GC are the lack of proper response to the treatment, drug resistance and metastasis attributed to the presence of a subpopulation of cells inside the tumour that are called cancer stem cells (CSCs).In addition, deregulation of mic

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